TOP PUBLICATIONS IN PHARMACEUTICAL MICROBIOLOGY AND BIOTECHNOLOGY
Here is a list of a few of our top publications. For a full list of publications from each of our research staff, please click on this link Pharmaceutical Microbiology and Biotechnology Staff and then on the staff name (in bold here) to see their profile and list of publications.
Prof. Charles O Esimone Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Nonye T. Ujam, Daniel L. Ajaghaku, Festus B.C. Okoye, Charles O. Esimone, Antioxidant and immunosuppressive activities of extracts of endophytic fungi isolated from Psidium guajava and Newbouldia laevis, Phytomedicine Plus, Volume 1, Issue 2, 2021, 100028, ISSN 2667-0313, https://doi.org/10.1016/j.phyplu.2021.100028
2. Ejikeugwu, C., Nworie, O., Saki, M. et al. Metallo-β-lactamase and AmpC genes in Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa isolates from abattoir and poultry origin in Nigeria. BMC Microbiol 21, 124 (2021). https://doi.org/10.1186/s12866-021-02179-1
3. M. C. Ugwu, M. Shariff , C.M. Nnajide, K Beri, U. M. Okezie, I. R. Iroha, and C. O. Esimone (2020). Phenotypic and Molecular Characterization of β-Lactamases among Enterobacterial Uropathogens in Southeastern Nigeria. Canadian Journal of Infectious Diseases and Medical Microbiology doi.org/10.1155/2020/5843904
Dr. Angus N Oli Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Oli AN, Edeh PA, Al-Mosawi RM, Mbachu NA, Al-Dahmoshi HOM, Al-Khafaji NSK, Ekuma UO, Okezie UM, Saki M. Evaluation of the phytoconstituents of Auriculariaauricula-judae mushroom and antimicrobial activity of its protein extract. Eur J Integr Med. 2020 Sep; 38:101176. https://doi.org/10.1016/j.eujim.2020.101176
2. Oli AN, Obialor WO, Ifeanyichukwu MO, Odimegwu DC, Okoyeh JN, Emechebe GO, Adejumo SA, Ibeanu GC. Immunoinformatics and Vaccine Development: An Overview. Immunotargets Ther. 2020 Feb 26;9:13-30. doi: 10.2147/ITT.S241064. PMID: 32161726; PMCID: PMC7049754.
3. Enemchukwu CM, Oli AN, Okoye EI, Ujam NT, Osazuwa EO, Emechebe GO, Okeke KN, Ifezulike CC, Ejiofor OS, Okoyeh JN. Winning the War against Multi-Drug Resistant Diarrhoeagenic Bacteria. Microorganisms. 2019 Jul 10;7(7):197. doi: 10.3390/microorganisms7070197. PMID: 31295889; PMCID: PMC6680719.
Dr. Malachy C Ugwu Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. C. S. Iroha, M. C. Ugwu , C. O. Esimone , I. R. Iroha , F. A. Ibiam and P. C. Ejikeugwu(2023) Molecular Characterization of Esbl and Colistin Resistance Genes Among Clinical Isolates of Gram-Negative Bacteria in A Tertiary Hospital In Abakaliki, Nigeria . IJPSR Vol. 14(6): 3063-3069. https://DOI: 10.13040/IJPSR.0975-8232.14(6).3063-69
2. Enebechi Charles Kenechukwu, Ugwu Malachy Chigozie, Nwobodo David Chinemerem, Enebechi Godson Uchenna, Emencheta Stephen Chijioke, Ugwu Chiamaka Belinda, Okoye Festus Basden Chiedu. Immunostimulatory and Antimicrobial Claims of Super-7 Herbal Mixture (SHM) and Odogwu Cleanser Herbal Mixture (OCHM) Commercially Available in Enugu State, Nigeria. American Journal of BioScience. Vol. 11, No. 1, 2023, pp. 11-20. https://doi: 10.11648/j.ajbio.20231101.12
3. Emekekwue AS, Ugwu MC, Ejikeugwu CP, Nwobodo DC, Ujam NT, Okezie UM, et al. Prevalence and Antibiogram of ESBL-positive Uropathogenic Escherichia coli in Pregnant Women in Onitsha Metropolis, Nigeria. Int J Pharm Phytopharmacol Res. 2022;12(6):8-18. https://doi.org/10.51847/x5e62APEMI
Dr. Linda O Anagu Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Linda O. Anagu, David R. Hulse, Paul D. Horrocks, Srabasti J. Chakravorty. Alteration of the expression of sirtuins and var genes by heat shock in the malaria parasite Plasmodium falciparum, Molecular and Biochemical Parasitology, Volume 248, 2022. https://doi.org/10.1016/j.molbiopara.2022.111458
2. Moses N Ikegbunam, Linda O Anagu, Carrisa Duru, Chukwuemeka S Nworu, Charles O Esimone, Olusola Ojurongbe (2022). Genetic diversity and allelic frequency of antigenic markers in Plasmodium falciparum isolates from Nnewi district in Nigeria. The Journal of Infection in Developing Countries, Vol 16(3), pp 557 – 563. https://doi.org/10.3855/jidc.14815
3. L Anagu, A A Attama, V C Okore, H T Gugu, A A Ngene, and C O Esimone. 2014. Azadirachta indica extract–artesunic acid combination produces increased cure rate of Plasmodium berghei-infected mice. Pharm Biol. 52(7): 883–889. https://doi.org/10.3109/13880209.2013.872153
Dr. Moses N. Ikegbunam Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Moses N Ikegbunam, Linda O Anagu, Carrisa Duru, Chukwuemeka S Nworu, Charles O Esimone, Olusola Ojurongbe (2022). Genetic diversity and allelic frequency of antigenic markers in Plasmodium falciparum isolates from Nnewi district in Nigeria. The Journal of Infection in Developing Countries, Vol 16(3), pp 557 – 563. https://doi.org/10.3855/jidc.14815
2. Ikegbunam, M.N., Anagu, L.O., Duru, C., Nworu, C.S., Esimone, C.O., & Ojurongbe, O. (2022). Genetic diversity and allelic frequency of antigenic markers in Plasmodium falciparum isolates from Nnewi district in Nigeria. Journal of infection in developing countries, 16 3, 557-563
3. Moses N Ikegbunam, Linda O Anagu, Carrisa Duru, Chukwuemeka S Nworu, Charles O Esimone, Olusola Ojurongbe (2022). Genetic diversity and allelic frequency of antigenic markers in Plasmodium falciparum isolates from Nnewi district in Nigeria. The Journal of Infection in Developing Countries, Vol 16(3), pp 557 – 563. https://doi.org/10.3855/jidc.14815
Dr. Chidimma R Chukwunwejim Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Ude, I. U., Moses, I. B., Okoronkwo, C., Ovia K., Okafor, C., Chukwunwejim, C. R.,Okata-Nwali, O. D., Iroha, C. S., Akuma, S., Peter, I. U., Uzoeto, H. O., Ngwu, J. N., Onuorah, A. L., John-Onwe, B. N and Iroha, I. R. (2021). Phytochemical properties and antimicrobial activity of Buchholzia coriacea and Psychotriamicrophylla leaf extracts on bacterial pathogens isolated from aquatic environments in Nigeria. Journal of Medicinal Plants Research, Vol. 15(6), 232-240
2. Ugbo, E.N., Anyamene, C.O., Moses, I.B., Iroha , I.R., Babalola, O.O., Ukpai , E.G., Chukwunwejim, C.R., Egbule, C.U.,Emioye, A.A., Okata-Nwali, O.D., Igwe, O.F. and Ugadu, I.O. (2020). Prevalence of blaTEM, blaSHV, and blaCTX-M genes among extended spectrum beta lactamase-producing Escherichia coli and Klebsiella pneumoniae of clinical origin. Gene Reports, 21: 100-909.
3. Ugbo, E. N., Anyamene, C. O., Moses, I. B., Ariom, T. O., Agumah, N. B., Chukwunwejim, C. R., Egbule, C. U., Emioye, A. A., Okata-Nwali, O. D., Aneke, C. J., Ugadu, I. O. and Osu, B. O. (2020). Isolation and molecular characteristics of extended spectrum beta-lactamase-producing uropathogenic Escherichia coli isolated from hospital attendees in Ebonyi State, Abakaliki. Afr. J. Biotechnol,19(11): 829-835
Uchenna C Ogwaluonye Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Ekwunife OI, Onubogu CU, Aribodor OB, … Ogwaluonye UC, et al. Approaching healthcare delivery through a new lens: a crowdsourcing challenge to identify health-related social innovations to increase universal health coverage in NigeriaBMJ Innovations 2022;8:207-215.
2. Eleje, G. U., Rabiu, A., Mbachu, I. I., Akaba, G. O., Loto, O. M., Usman, H. A., Fiebai, P. O., Joe-Ikechebelu, N. N., Ogwaluonye U. C., et al.. (2021). Awareness And Prevalence Of Hepatitis C Virus Infection Among Pregnant Women In Nigeria: A National Pilot Cross-sectional Study. Women’s Health, Vol. 17.
3. Eleje, G. U., Rabiu, A., Mbachu, I. I., Akaba, G. O., Loto, O. M., Usman, H. A., Fiebai, P. O., Joe-Ikechebelu, N. N., Ogwaluonye U. C., et al. (2021). Pregnant Women’s Hepatitis B Vaccination Coverage In Nigeria: A National Pilot Cross-sectional Study. Therapeutic Advances in Vaccines and Immunotherapy., Vol. 9.
Dr. Ugochukwu M. Okezie Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Ugochukwu M. Okezie, Peter M. EZE, Festus B.C. OKOYE, Charles O. ESIMONE. (2022). Orthosporin, a major component of the fermentation product of Lasiodiplodia theobromae- an endophytic fungus of Musa paradisiaca as a potential antimicrobial agent. Notulae Scientia Biologicae. Vol. 14:2. DOI:10.15835/nsb14211084
2. Nzekwe IT, Agwuka OI, Okezie MU, Fasheun DO, Nnamani PO, Agubata CO. Designing an ideal alcohol-based hand sanitizer: in vitro antibacterial responses of ethanol and isopropyl alcohol solutions to changing composition. AAPS Open. 2021;7(1):5. https://doi.org/10.1186/s41120-021-00038-x
3. Chigozie VU, Okezie MU, Ajaegbu EE, Okoye FB, Esimone CO. Bioactivities and HPLC analysis of secondary metabolites of a morphologically identified endophytic Aspergillus fungus isolated from Mangiferaindica. Nat Prod Res. 2022 Nov;36(22):5884-5888. https://doi.org/10.1080/14786419.2021.2021517
Augustine Onwuduba Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Onwunduba A, Ekwunife O, Onyilogwu E. Impact of point-of-care C-reactive protein testing intervention on non-prescription dispensing of antibiotics for respiratory tract infections in private community pharmacies in Nigeria: a cluster randomized controlled trial. Int J Infect Dis 2023; 127: 137-143. doi: 10.1016/j.ijid.2022.12.006.
Chinelo K. Ezejiegu Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Chinelo K. Ezejiegu, Angus N. Oli, Chinwendu N. Ezomike, Christian C. Uba, Uchenna C. Ogwaluonye, Charles O. Esimone. (2022, November), “Artemether-Lumefantrine Combination for Non-Comorbid Falciparum Malaria: A Clinico-Parasitological Efficacy Study”, Journal of Tropical Journal of Natural Product Research Biochemical Research, Vol. 6, (Issue 10)
2. Ifeanyi Peter Onyeka, Felix Ahamefule Onyegbule, Christopher Obodike Ezugwu, Emeka John Dingwoke, Chibueze Jeremiah Ike, Cyril Onyeka Ogbue, Chinelo Kene Ezejiegu, Chiamaka Henrietta Jibuaku. (2022, July), “Gastroprotective effects of Methanol leaf extract of Desmodiumvelutinum (Fabaceae) and honey on ethanol-induced gastric ulcer in albino rat: The concept of combination therapy”, GSC Biological and Pharmaceutical Sciences, Vol. 20, (Issue 1), pp 167–181
3. Ugochukwu Moses Okezie, Adaora Chinwe Evelyn Okoye, Nnamdi Markben Adione , Chinelo Kenechukwu Ezejiegu , OgechiOzioma Anyanwu , Kenneth Gerald Ngwoke , Angus Nnamdi Oli , Malachy Chigozie Ugwu , Festus Basden Chiedu Okoye , Charles Okechukwu Esimone. (2022, January), “The Antibiogram of Pyocyanin-Producing Laboratory and Environmental Pseudomonas aeruginosa Isolates”, Journal of Current Biochemical Research, Vol. 1, (Issue 4)
Dr. Ijeoma N. Ebenebe Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Okafor C.M., Ikegbunam M.N., Nwachukwu J.C., Ebenebe Ijeoma N. and Nnanna J.C. Prevalence of Antibiotic Resistant Bacteria in Nigerian Fermented Food Condiments. Journal of Biology and Life Science 2020; 11(1): 110-120.
2. Ijeoma Ngozi Ebenebe, Uduma Eke Osonwa, Charles Okechukwu Esimone, Kingsley C Anukam. Development and Evaluation of Vaginal Suppository Containing Lactiplantibacillus pentosus KCA1 for Treatment of Bacterial Vaginosis: Can Fourier Transform-Infrared (FT-IR) Spectroscopy be Used for Identification of Lactiplantibacillus pentosus KCA1? Journal of Medical Laboratory Science, 2021a; 31 (2): 52-72.
3. Ijeoma Ngozi Ebenebe, Uduma Eke Osonwa, Chidimma Ruth Chukwunwejim, Ugonna Chinwe Morikwe, Joy Ogugua Igwe, Charles O Esimone and Kingsley C Anukam. Assessment of vaginal health before and after treatment with vaginal suppository containing Lactiplantibacillus pentosus KCA1. GSC Biological and Pharmaceutical Sciences. 2021b; 17(01): 105–112.
Dr. Miriam N Anejionu Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Okezie UM, Obi MC, Morikwe UC, Ebenebe IN, Nwaneri MGU. Antimicrobial and antioxidant potentials of crude extracts of culturally dissimilar endophytic fungi. GSC Biological and Pharmaceutical Sciences. 2022 Dec 22(02), 187–195. DOI: https://doi.org/10.30574/gscbps.2023.22.2.0475.
2. Anejionu MGU, Oli AN, Ezeudu CE, Ezejiofor OI, Ezeogu J, Attama AA, Okore VC. Methicillin-Resistant Staphylococcus
aureus May Also Be Resistant to Clindamycin and Vancomycin. Journal of Biosciences and Medicines 2022 Aug 10, 1-13. 13. https://doi.org/10.4236/jbm.2022.108001.
3. Anejionu OCD, Ebinne ES, Nwosu KI Anejinou MGU, Ndukwu RI. Are residents in urban areas of nigeria exposed to health-impacting levels of noise pollution? Journal of Environmental Science and Sustainable Development. 2022 Jul 5(1), 85-108. https://doi.org/10.7454/jessd.v5i1.1096
Jibuaku Chiamaka Link: https://pharmacy.unizik.edu.ng/wp-admin/post.php?post=1228&action=edit
1. Quraishi, E., Jibuaku, C., Lisik, D. et al. Comparison of clinician diagnosis of COVID-19 with real time polymerase chain reaction in an adult-representative population in Sweden. Respir Res 24, 10 (2023). https://doi.org/10.1186/s12931-023-02315-7
2. D Lisik, C Jibuaku, E Quraishi, H Kankaanranta, B I Nwaru (2022). Does the accuracy of clinician diagnosis of COVID-19 compared to RT-PCR in adults depend on the number and severity of comorbidities? European Respiratory Journal 2022 60: 1537; DOI: 10.1183/13993003.congress-2022.1537
3. C Jibuaku, E Quraishi, D Lisik, H Kankaanranta, B Nwaru, D Lisik (2022). Comparison of clinician diagnosis of COVID-19 against real-time polymerase chain reaction in a general adult population. European Respiratory Journal 2022 60: 2123; DOI: 10.1183/13993003.congress-2022.2123